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Related Concept Videos

Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
Epistasis01:39

Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
Mate Choice01:20

Mate Choice

Mate choice—the decision about whom to mate with—is a type of natural selection, since animals must reproduce to pass down their genes. Mate choice is also called intersexual selection because the behavior occurs between the sexes.
Monohybrid Crosses01:20

Monohybrid Crosses

Overview
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

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Related Experiment Video

Updated: Jun 3, 2026

Manipulation of Color Patterns in Jumping Spiders for Use in Behavioral Experiments
09:03

Manipulation of Color Patterns in Jumping Spiders for Use in Behavioral Experiments

Published on: May 21, 2019

Colours of domestication.

Michael Cieslak1, Monika Reissmann, Michael Hofreiter

  • 1Leibniz Institute for Zoo and Wildlife Research, Research Group of Evolutionary Genetics, Berlin, Germany.

Biological Reviews of the Cambridge Philosophical Society
|March 30, 2011
PubMed
Summary
This summary is machine-generated.

Domesticated mammals show greater coat color variation due to artificial selection acting on coat-color genes. This review explores the genetic basis and molecular mechanisms behind this increased diversity in animal pigmentation.

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Area of Science:

  • Genetics
  • Animal Science
  • Evolutionary Biology

Background:

  • Coat coloration in mammals is a widely studied trait, particularly in domesticated species.
  • Domesticated animals exhibit greater allelic variability in coat-color genes compared to wild ancestors, driven by artificial selection.
  • Over 300 genetic loci and 150 coat-color genes are known, but underlying genetic pathways remain incompletely understood.

Purpose of the Study:

  • To investigate the causes of increased coat color variation in domesticated animals.
  • To review the current understanding of molecular mechanisms influencing mammalian coat coloration.
  • To examine the timing and location of action for coat-color-associated genes.

Main Methods:

  • Literature review focusing on genetic studies of mammalian coat coloration.
  • Analysis of artificial selection pressures on coat-color phenotypes during domestication.
  • Synthesis of current knowledge on gene function and regulation in pigmentation pathways.

Main Results:

  • Artificial selection, starting from domestication, has led to increased allelic variability and diverse coat colors in domestic animals, often accepting pleiotropic effects.
  • Phenotypically similar coat colors can arise from different genetic bases across species or individuals.
  • Conserved genes can underlie similar coat colorations in different species.

Conclusions:

  • Understanding the genetic basis of coat color requires moving beyond phenotypic classification.
  • Further research is needed to fully elucidate the complex genetic pathways and gene interactions governing mammalian pigmentation.
  • The review highlights the evolutionary and molecular factors contributing to the rich diversity of coat colors in domesticated mammals.