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Using An In Vitro Tissue Perfusion System to Detect the Functional Activities of Isolated Intestinal Tubes in Real Time
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Published on: July 26, 2024

Food intolerance in functional bowel disorders.

Peter R Gibson1

  • 1Eastern Health Clinical School, Monash University and Eastern Health, Box Hill, Victoria, Australia. peter.gibson@monash.edu

Journal of Gastroenterology and Hepatology
|March 30, 2011
PubMed
Summary

Dietary modification targeting Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) is an effective therapy for functional bowel disorders. A low FODMAP diet, delivered by trained dietitians, should be considered a first-line treatment for most patients.

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Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

Area of Science:

  • Gastroenterology
  • Dietary Science
  • Clinical Nutrition

Background:

  • Food-related symptoms are prevalent in functional bowel disorders (FBD).
  • Dietary interventions are not consistently integrated into routine FBD management.
  • This review discusses evidence-based dietary strategies for FBD.

Purpose of the Study:

  • To review and discuss commonly applied dietary strategies for functional bowel disorders.
  • To evaluate the evidence supporting different dietary approaches for FBD symptom management.

Main Methods:

  • A comprehensive review of published literature was conducted.
  • The review focused on various dietary interventions for functional bowel disorders.

Main Results:

  • Traditional elimination diets are often impractical for routine use.
  • Pathogenically-based approaches targeting specific food hypersensitivities show limited success.
  • The low Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) diet, delivered by dietitians, demonstrates high-quality evidence of efficacy, improving symptoms in a majority of FBD patients.
  • The low FODMAP diet may also benefit patients with inflammatory bowel disease and those with ileal pouch or high output ileostomy.

Conclusions:

  • Dietary restriction of FODMAPs is a highly effective therapy for the majority of patients experiencing functional bowel symptoms.
  • A dietitian-delivered low FODMAP diet should be considered a first-line therapeutic strategy for FBD, contingent upon appropriate dietitian training.