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Related Experiment Video

Updated: Jun 3, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

Factor deficiencies in pregnancy.

Gillian N Pike1, Paula H B Bolton-Maggs

  • 1Department of Clinical Haematology, Manchester Royal Infirmary, Manchester, UK.

Hematology/Oncology Clinics of North America
|March 30, 2011
PubMed
Summary
This summary is machine-generated.

Managing pregnant women with inherited bleeding disorders requires careful attention during pregnancy, delivery, and postpartum. This review offers guidance for various factor deficiencies, including hemophilia carriers.

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Last Updated: Jun 3, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
03:19

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes

Published on: June 28, 2024

Area of Science:

  • Obstetrics and Gynecology
  • Hematology
  • Reproductive Medicine

Background:

  • Pregnancy presents unique hemostatic challenges for women with bleeding disorders.
  • Inherited coagulation disorders can complicate pregnancy, childbirth, and the puerperium.
  • Effective management is crucial for maternal and fetal well-being.

Purpose of the Study:

  • To provide general recommendations for managing pregnant women with inherited coagulation disorders.
  • To review current literature and offer guidance for specific factor deficiencies.
  • To address the management of carriers of hemophilia A and B.

Main Methods:

  • Literature review of inherited coagulation disorders in pregnancy.
  • Discussion of management strategies for specific factor deficiencies.
  • Guidance on care throughout pregnancy, delivery, and the puerperium.

Main Results:

  • Detailed discussion of management for fibrinogen abnormalities, prothrombin, factor V, VII, X, XI, XIII deficiencies.
  • Coverage of combined factor V and VIII deficiencies.
  • Inclusion of vitamin K-dependent clotting factor deficiencies and hemophilia carriers.

Conclusions:

  • Comprehensive management guidelines are essential for pregnant women with bleeding disorders.
  • Tailored approaches are necessary for each specific factor deficiency.
  • This review serves as a resource for optimizing care during the peripartum period.