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The regulation of gene expression and the molecular basis of cancer
1Laboratoire de recherche sur le cancer et les maladies du sang, Zone industrielle Grasbusch, Leudelange, Luxembourg.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|January 1, 1990
Abstract:
Over the last few years, the advent of new genetic techniques allowed a detailed analysis of the structural and functional organization of the genome and the genes in a living cell. After the discovery of cellular oncogenes, genes which are implicated in cell growth control and differentiation, recent investigations provided evidence to a crucial role played by certain gene regulatory DNA elements and oncoproteins in the molecular mechanisms of carcinogenesis.