Cell cycle-dependent phosphorylation of pRb-like protein in root meristem cells of Vicia faba
Related Experiment Video
Updated: Jun 3, 2026

High Resolution Quantification of Crystalline Cellulose Accumulation in Arabidopsis Roots to Monitor Tissue-specific Cell Wall Modifications
Published on: May 10, 2016
Justyna Teresa Polit1, Andrzej Kaźmierczak, Aurelia Walczak-Drzewiecka
1Department of Cytophysiology, University of Łódź, Łódź, Poland. justpoli@poczta.onet.pl
Abstract:
The retinoblastoma tumor suppressor protein (pRb) regulates cell cycle progression by controlling the G1-to-S phase transition. As evidenced in mammals, pRb has three functionally distinct binding domains and interacts with a number of proteins including the E2F family of transcription factors, proteins with a conserved LxCxE motif (D-type cyclin), and c-Abl tyrosine kinase. CDK-mediated phosphorylation of pRb inhibits its ability to bind target proteins, thus enabling further progression of the cell cycle. As yet, the roles of pRb and pRb-binding factors have not been well characterized in plants. By using antibody which specifically recognizes phosphorylated serines (S807/811) in the c-Abl tyrosine kinase binding C-domain of human pRb, we provide evidence for the cell cycle-dependent changes in pRb-like proteins in root meristems cells of Vicia faba. An increased phosphorylation of this protein has been found correlated with the G1-to-S phase transition.
More Related Videos
10:58Plant Promoter Analysis: Identification and Characterization of Root Nodule Specific Promoter in the Common Bean
Published on: December 23, 2017
08:31Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves
Published on: December 2, 2016
Related Concept Videos
Cell Signaling in Plants
Negative Regulator Molecules
Cells Coordinate Growth and Proliferation
Cells Coordinate Growth and Proliferation
DNA Damage can Stall the Cell Cycle
DNA Damage Can Stall the Cell Cycle