Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 3, 2026

Oropharyngeal Administration of Bleomycin in the Murine Model of Pulmonary Fibrosis
06:03

Oropharyngeal Administration of Bleomycin in the Murine Model of Pulmonary Fibrosis

Published on: May 9, 2025

Distribution of bleomycin in a rat model.

P Engström1, L G Salford, B R Persson

  • 1Department of Radiation Physics, Lund University Hospital, Lund, Sweden.

Methods in Molecular Medicine
|March 30, 2011
PubMed
Summary

Bleomycin is a potent chemotherapy drug frequently used with electrochemotherapy (ECT) for cancer treatment. This study investigates bleomycin

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Copepods drive large-scale trait-mediated effects in marine plankton.

Science advances·2019
Same author

Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015.

Journal of labelled compounds & radiopharmaceuticals·2016
Same author

Production of transgenic pea (Pisum sativum L.) plants by Agrobacterium tumefaciens - mediated gene transfer.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same author

Inheritance of a bacterial hygromycin phosphotransferase gene in the progeny of primary transgenic pea plants.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same author

Cytokinin treatment of embryos inhibits the synthesis of chloroplast proteins in Norway spruce.

Planta·2013
Same author

Treatment of rat glioma with electrochemotherapy.

Methods in molecular medicine·2011

Area of Science:

  • Oncology
  • Pharmacology
  • Cancer Therapeutics

Background:

  • Bleomycin is a widely used and effective chemotherapeutic agent.
  • Electrochemotherapy (ECT) is a cancer treatment modality that enhances drug delivery.
  • Bleomycin is the most common agent used in ECT.

Purpose of the Study:

  • To investigate the pharmacokinetics of bleomycin.
  • To understand bleomycin behavior under normal conditions.
  • To analyze bleomycin pharmacokinetics specifically during ECT.

Main Methods:

  • Pharmacokinetic analysis of bleomycin.
  • Comparative study of bleomycin behavior with and without ECT.

Main Results:

  • Detailed pharmacokinetic data for bleomycin was collected.
  • Specific alterations in bleomycin pharmacokinetics during ECT were identified.

Conclusions:

  • Bleomycin exhibits specific pharmacokinetic properties.
  • Understanding these properties is crucial for optimizing ECT efficacy.
  • Further research can refine bleomycin-based cancer therapies.

More Related Videos

A Refined Aerosol-Based Intratracheal Bleomycin Delivery Method for Reproducible and Minimally Invasive Mouse Models of Pulmonary Fibrosis
05:45

A Refined Aerosol-Based Intratracheal Bleomycin Delivery Method for Reproducible and Minimally Invasive Mouse Models of Pulmonary Fibrosis

Published on: January 16, 2026

A Mouse Model of Pulmonary Fibrosis Induced by Nasal Bleomycin Nebulization
02:46

A Mouse Model of Pulmonary Fibrosis Induced by Nasal Bleomycin Nebulization

Published on: January 20, 2023

Related Experiment Videos

Last Updated: Jun 3, 2026

Oropharyngeal Administration of Bleomycin in the Murine Model of Pulmonary Fibrosis
06:03

Oropharyngeal Administration of Bleomycin in the Murine Model of Pulmonary Fibrosis

Published on: May 9, 2025

A Refined Aerosol-Based Intratracheal Bleomycin Delivery Method for Reproducible and Minimally Invasive Mouse Models of Pulmonary Fibrosis
05:45

A Refined Aerosol-Based Intratracheal Bleomycin Delivery Method for Reproducible and Minimally Invasive Mouse Models of Pulmonary Fibrosis

Published on: January 16, 2026

A Mouse Model of Pulmonary Fibrosis Induced by Nasal Bleomycin Nebulization
02:46

A Mouse Model of Pulmonary Fibrosis Induced by Nasal Bleomycin Nebulization

Published on: January 20, 2023