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Updated: Jun 3, 2026

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light
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An in-mold packaging process for plastic fluidic devices.

Y E Yoo1, K H Lee, T J Je

  • 1Nano-Mechanical Systems Research Division, Korea Institute of Machinery and Materials, Daejeon 305-343, Korea.

Journal of Nanoscience and Nanotechnology
|March 31, 2011
PubMed
Summary
This summary is machine-generated.

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This study introduces a novel molding process to create enclosed microfluidic and nanofluidic devices without traditional solid-to-solid bonding. This method offers a faster, more efficient alternative for mass production of microfluidic and nanofluidic systems.

Area of Science:

  • Microfluidics and Nanofluidics
  • Materials Science
  • Manufacturing Engineering

Background:

  • Micro and nanofluidic devices require enclosed channels to prevent fluid leakage.
  • Conventional methods like solid-to-solid bonding for fabricating enclosed channels are time-consuming and unsuitable for mass production.

Purpose of the Study:

  • To propose and assess the feasibility of a new molding process for creating enclosed micro/nanochannels without solid-to-solid bonding.
  • To optimize process and mold design parameters for effective cover layer molding.
  • To evaluate the bond strength and seal performance of the molded covers compared to conventional methods.

Main Methods:

  • Fabrication of a brass microchannel master core based on a model design.
  • Injection molding of a plastic microchannel platform using the master core.

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Last Updated: Jun 3, 2026

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light
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Published on: August 17, 2017

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
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  • Experimental investigation of four process and mold design parameters for cover layer molding.
  • Assessment of bond strength and seal performance of the molded enclosed channels.
  • Main Results:

    • Successful identification of feasible conditions for molding a cover layer over a plastic microchannel platform, enclosing the channels without filling them.
    • Demonstration of a novel molding technique as an alternative to conventional bonding or welding.
    • Comparative estimation of bond strength and seal performance against traditional methods.

    Conclusions:

    • The proposed molding process is a feasible and potentially more efficient method for fabricating enclosed micro and nanofluidic devices.
    • This technique offers a viable alternative for mass production, overcoming the limitations of time-consuming conventional bonding processes.
    • Further optimization and characterization can enhance the application of this molding process in microfluidic device manufacturing.