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07:22
Bacteriophage Effectiveness for Biocontrol of Foodborne Pathogens Evaluated via High-Throughput Settings
Published on: August 19, 2021
Campylobacter bacteriophages and bacteriophage therapy
P L Connerton1, A R Timms, I F Connerton
1School of Biosciences, Division of Food Sciences, University of Nottingham, Loughborough Leics, UK.
Journal of Applied Microbiology
|March 31, 2011
Summary
Campylobacter bacteria cause human enteric disease, often from poultry. Campylobacter-specific bacteriophages offer a novel therapeutic approach to reduce pathogen levels in poultry and food.
Area of Science:
- Microbiology
- Food Safety
- Veterinary Science
Background:
- Campylobacter species are a leading cause of human enteric disease, with poultry products identified as a major transmission source.
- High prevalence of Campylobacter in poultry flocks (over 80% in the UK) necessitates effective control strategies.
Purpose of the Study:
- To provide a comprehensive review of Campylobacter-specific bacteriophages.
- To explore their potential as therapeutic agents for reducing Campylobacter in poultry and for food bio-sanitization.
Main Methods:
- Review of historical data on bacteriophage isolation and characterization.
- Analysis of genomic data of Campylobacter bacteriophages.
- Examination of their application in poultry farming and food safety.
Main Results:
- Campylobacter bacteriophages have been isolated since the 1960s and used in typing schemes.
- Genomic characterization reveals insights into their host interactions.
- Bacteriophages show promise for reducing Campylobacter in poultry and for food bio-sanitization.
Conclusions:
- Campylobacter-specific bacteriophages represent a promising biological control agent against a significant foodborne pathogen.
- Further research into their application can enhance food safety and reduce public health risks associated with Campylobacter infections.
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