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Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Decrease in cerebral and cerebellar gray matter in essential tremor: a voxel-based morphometric analysis under 3T

Bhavani Shankara Bagepally1, Maya Dattatraya Bhatt, Vijay Chandran

  • 1Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health & Neurosciences, Bangalore, Karnataka, India.

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
|March 31, 2011
PubMed
Summary
This summary is machine-generated.

Essential tremor (ET) patients exhibit brain atrophy, particularly in the cerebellum and cerebral gray matter (GM). Head tremor may indicate a distinct ET subgroup, with atrophy linked to tremor severity.

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Area of Science:

  • Neuroimaging
  • Neurology
  • Neuroscience

Background:

  • Essential tremor (ET) often presents with normal routine neuroimaging.
  • Clinical evidence suggests widespread central nervous system involvement in ET.

Purpose of the Study:

  • To determine morphological brain changes in ET patients using voxel-based morphometry (VBM).
  • To compare subtypes of Essential Tremor.

Main Methods:

  • Voxel-based morphometry (VBM) analysis of T1W volumetric MRI data.
  • Comparison of 20 ET patients with 17 matched control subjects.
  • Statistical Parametric Mapping 5 (SPM5) software was utilized.

Main Results:

  • ET patients showed scattered cerebral and cerebellar gray matter (GM) atrophy compared to controls.
  • Patients with head tremor displayed widespread GM atrophy in cerebral hemispheres.
  • No significant difference in atrophy was observed between familial and nonfamilial ET subgroups.
  • A relationship was found between GM atrophy and tremor severity score.

Conclusions:

  • Widespread cerebral and cerebellar GM atrophy in ET supports its progressive and diffuse nature.
  • Essential tremor patients with head tremor might represent a distinct subgroup.
  • VBM analysis is effective in detecting subclinical brain changes in ET.