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Updated: Jun 3, 2026

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation
Published on: August 26, 2011
[Total body scan: struggle between emotion and science].
1Universitair Medisch Centrum Utrecht, afd. Radiologie, Utrecht, The Netherlands. w.mali@umcutrecht.nl
Commercial health screening using CT and MRI for asymptomatic diseases lacks proven benefit and may cause harm. Costs associated with false positives and unproven tests outweigh potential advantages for individuals and healthcare systems.
Area of Science:
- Medical imaging technologies
- Preventive medicine
- Health economics
Context:
- Commercial screening centers emerged in the late 1990s.
- Initial focus on asymptomatic tumors and cardiovascular diseases using CT and MRI.
- Expansion to broader screening packages including PSA and pulmonary/cardiac function tests.
Purpose:
- To evaluate the utility and potential harms of commercial health screening for asymptomatic conditions.
- To assess the economic implications of false positive findings in widespread screening programs.
Summary:
- Despite the appeal of early detection, current research raises significant doubts about the effectiveness of commercial screening for asymptomatic individuals.
- The high costs of managing false positive results, often covered by general health insurance, are a major concern.
- Lack of data on the usefulness of newer screening packages, including PSA and cardiopulmonary tests, suggests potential harm rather than benefit.
Impact:
- Widespread commercial screening may lead to unnecessary medical interventions and increased healthcare expenditures.
- Further research is needed to establish the clinical utility and cost-effectiveness of these screening practices.
- Potential for patient harm due to anxiety and invasive follow-up procedures resulting from false positive screening results.
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