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Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R
Published on: December 9, 2022
Type -2 diabetes mellitus and auditory brainstem responses-a hospital based study
Rahul Gupta1, Mohd Aslam, Sa Hasan
1Department of Otorhinolaringology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh- 202002.
Indian Journal of Endocrinology and Metabolism
|March 31, 2011
Summary
Brainstem auditory evoked response (BAER) testing reveals early central nervous system (CNS) and acoustic nerve pathway damage in diabetes mellitus patients. This non-invasive method aids in detecting subclinical neurological involvement in diabetes.
Area of Science:
- Neurology
- Audiology
- Endocrinology
Background:
- Diabetes mellitus (DM) is characterized by hyperglycemia, leading to widespread organ damage.
- Metabolic dysregulation in DM affects multiple organ systems, including the central nervous system (CNS).
- Brainstem auditory evoked response (BAER) is a non-invasive technique to assess auditory pathways and CNS integrity.
Purpose of the Study:
- To investigate subclinical auditory pathway and CNS involvement in patients with diabetes mellitus.
- To evaluate the utility of BAER in early detection of neurological complications in diabetic patients.
Main Methods:
- A comparative study involving 25 diabetic patients and 25 healthy controls.
- Brainstem auditory evoked response (BAER) testing was performed using IHS-BERA equipment.
- Auditory evoked potentials were recorded at different decibel levels (70, 80, and 90 dB).
Main Results:
- Significant differences in wave latencies and interpeak intervals (I-III, III-V, I-V) were observed between diabetic and control groups at various decibel levels.
- Specifically, highly significant differences were noted in wave V latency and interpeak intervals I-III and I-V.
- These findings indicate early impairment in the central auditory pathways of diabetic individuals.
Conclusions:
- BAER is a valuable, non-invasive tool for detecting early acoustic nerve and CNS pathway dysfunction in diabetic patients.
- BAER can identify subclinical neurological involvement in the auditory system, even before overt symptoms appear.
- Routine BAER screening in diabetic populations may facilitate earlier diagnosis and management of neurological complications.
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