Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Excess Pressure Inside a Drop and a Bubble

Excess Pressure Inside a Drop and a Bubble

The shape of a small drop of liquid can be considered spherical, neglecting the effect of gravity. This drop can further be considered as two equal hemispherical drops put together due to surface tension. The forces acting on the spherical drop are due to the pressure of the liquid inside the drop, the pressure due to air outside the drop, and the force due to the surface tension acting on the two hemispherical drops.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Spatially resolved transcriptome-metabolome integration reveals region-specific glial lipid dysregulation associated with Alzheimer's pathology.

bioRxiv : the preprint server for biology·2026

Same author

PURE-seq integrates FACS and PIP-seq for single-cell genomics of ultra-rare cells.

Nature communications·2026

Same author

Deterministic cell pairing with simultaneous microfluidic merging and sorting of droplets.

Lab on a chip·2025

Same author

Tumor heterogeneity underlies clinical outcome and MEK inhibitor response in somatic NF1-mutant glioblastoma.

JCI insight·2025

Same author

Myeloid-mesenchymal crosstalk drives ARG1-dependent profibrotic metabolism via ornithine in lung fibrosis.

The Journal of clinical investigation·2025

Same author

Comprehensive Cross-Domain Taxonomic Classification of Microbiotas using Partitioned Amplification Multiplexed Amplicon Sequencing (PAMA-seq).

bioRxiv : the preprint server for biology·2025

Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026

Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026

Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026

Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026

Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026

Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

Air-bubble-triggered drop formation in microfluidics.

Adam R Abate¹, David A Weitz

¹School of Engineering and Applied Sciences/Department of Physics, Harvard University, Cambridge, Massachusetts, USA. adam.abate@ucsf.edu

|March 31, 2011

Summary

This summary is machine-generated.

Researchers developed a novel microfluidic drop formation method that bypasses the jetting transition, enabling significantly faster production rates compared to traditional T-junction and flow-focus techniques.

More Related Videos

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

Glass-Based Devices to Generate Drops and Emulsions

Glass-Based Devices to Generate Drops and Emulsions

Published on: April 5, 2022

Related Experiment Videos

Last Updated: Jun 3, 2026

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

Glass-Based Devices to Generate Drops and Emulsions

Glass-Based Devices to Generate Drops and Emulsions

Published on: April 5, 2022

Area of Science:

Microfluidics
Fluid Dynamics
Chemical Engineering

Background:

Traditional microfluidic droplet generation relies on T-junction or flow-focus mechanisms.
These methods offer control but are limited by the jetting transition, restricting maximum production rates.

Purpose of the Study:

To introduce and characterize a new droplet formation mechanism for microfluidic devices.
To overcome the production rate limitations imposed by the jetting transition in existing methods.

Main Methods:

Development of a novel microfluidic device architecture.
Experimental investigation of droplet formation dynamics under varying flow conditions.
High-speed imaging to analyze droplet generation and characterize the new mechanism.

Main Results:

Demonstration of a new droplet formation mechanism independent of the jetting transition.
Achieved significantly higher droplet production rates compared to conventional methods.
Characterization of the operational window for the novel mechanism.

Conclusions:

The new mechanism provides a pathway for substantially increasing droplet production in microfluidics.
This advancement has potential applications in high-throughput screening, synthesis, and diagnostics.
Offers a scalable solution for microfluidic droplet generation beyond current limitations.