Primary cardiac osteosarcoma with imaging that revealed no calcification

Area of Science:

• Cardiology
• Oncology
• Pathology

Background:

• Osteosarcoma is a rare primary cardiac malignancy.
• Imaging calcification is a key diagnostic feature for cardiac osteosarcoma.

Observation:

• A 67-year-old male presented with heart failure, echocardiography revealed a left atrial mass.
• Computed tomography (CT) imaging showed no calcification, complicating the diagnosis.

Findings:

• Surgical resection and subsequent histopathological examination confirmed the left atrial mass as osteosarcoma.
• This case highlights a rare presentation of cardiac osteosarcoma lacking typical imaging calcification.

Implications:

• The findings underscore the importance of considering osteosarcoma in cardiac masses, even without calcification.
• This case emphasizes the need for integrated diagnostic approaches combining imaging and histopathology for rare cardiac tumors.