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Updated: Jun 3, 2026

05:23
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Transfusion practice in trauma patient]
Bojan Jovanović1, Vesna Bumbasirević, Milena Pandurović
1Klinika za anesteziologiju i reanimatologiju KCS, Medicinski fakultet Beograd.
Acta Chirurgica Iugoslavica
|April 1, 2011
Summary
Anemia is common in critically ill patients. Clinical guidelines suggest specific hemoglobin triggers for packed red blood cell (PRBC) transfusions to balance anemia risks with transfusion risks.
Area of Science:
- Critical Care Medicine
- Hematology
Background:
- Anemia is prevalent in critically ill patients, potentially worsening outcomes.
- Red blood cell transfusion carries inherent risks, necessitating careful risk-benefit assessment.
Purpose of the Study:
- To outline clinical practice guidelines for red blood cell transfusion in critically ill patients.
- To establish transfusion triggers balancing anemia and transfusion risks.
Main Methods:
- Review of recent studies comparing liberal versus restrictive transfusion strategies.
- Development of clinical practice protocols for stable intensive care unit patients without active bleeding.
Main Results:
- Guidelines recommend specific hemoglobin thresholds for packed red blood cell (PRBC) transfusion.
- Protocols are designed for patients post-resuscitation, stable in the ICU.
Conclusions:
- Clinical practice guidelines provide a framework for transfusion decisions in critically ill patients.
- Transfusion triggers aim to optimize patient outcomes by managing anemia and transfusion-related risks.
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