Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Low-dose sufentanil in major surgery.

L Perreault1, D Vézina, K Roberts

  • 1Department of Anaesthesia, Maisonneuve-Rosemont Hospital, University of Montreal, Quebec.

Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nutrition Support in Critically Ill Adults in Intensive Care Units: An Evidence Analysis Center Scoping Review of Current Systematic Reviews and Guidelines.

Journal of the Academy of Nutrition and Dietetics·2026
Same author

Shaping a better future for children living with rare diseases: The pivotal role of paediatric nurses.

Journal of pediatric nursing·2025
Same author

Resolution in Two-Photon Imaging: A Local Manifestation of Entanglement.

ACS photonics·2025
Same author

CT and MRI activity in England: insights from the diagnostic imaging dataset.

Clinical radiology·2025
Same author

A cognitive help or hindrance? A systematic review of cognitive behavioural therapy to treat anxiety in young people with autism spectrum disorder.

Clinical child psychology and psychiatry·2025
Same author

Optimising detector readout settings for the detection of spatial correlations between SPDC photon-pairs.

Scientific reports·2025

Sufentanil anesthesia provided good cardiovascular stability during major non-cardiac surgery. This technique ensured effective pain management with minimal respiratory depression and acceptable side effects like nausea and vomiting.

Area of Science:

  • Anesthesiology
  • Pharmacology

Background:

  • Sufentanil is a potent opioid analgesic used in anesthesia.
  • Optimizing anesthetic techniques for major non-cardiac surgery is crucial for patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy of sufentanil (1 microgram.kg-1) combined with nitrous oxide-oxygen and intermittent isoflurane anesthesia.
  • To assess cardiovascular stability and respiratory effects during major non-cardiac surgery.

Main Methods:

  • Thirty-one patients undergoing cholecystectomy received sufentanil before anesthesia induction.
  • Cardiovascular parameters and respiratory status were monitored throughout the procedure.
  • Isoflurane was administered as needed for cardiovascular stability.

Main Results:

Related Experiment Videos

  • Arterial pressure decreased post-sufentanil, but clinically significant hypertension or hypotension did not occur.
  • Postoperative respiratory depression was absent in patients receiving less than 1 microgram.kg-1.hr-1 of sufentanil, with the last dose >20 min before recovery.
  • Nausea (35%) and vomiting (23%) were the most common side effects. Anesthesia was rated good or satisfactory in most cases.

Conclusions:

  • Sufentanil combined with N2O-O2 and intermittent isoflurane anesthesia is effective for major non-cardiac surgery.
  • This technique provides good cardiovascular protection without significant respiratory depression during recovery.
  • The anesthetic approach is valuable for managing major non-cardiac surgical procedures.