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Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial
Nicholas J Glasgow1, Anne-Louise Ponsonby, Andrew Kemp
1The Australian National University, Acton, 0200 ACT, Australia. nicholas.glasgow@anu.edu.au
Insights
Introducing feather bedding to children with asthma did not improve respiratory symptoms or lung function compared to standard care. This randomized controlled trial found no significant differences in wheezing or sleep disturbances over one year.
Area of Science:
- Allergy and Immunology
- Respiratory Medicine
- Clinical Trials
Background:
- Observational studies suggest feather bedding may reduce asthma symptoms.
- However, no randomized controlled trials (RCTs) have evaluated feather bedding as a secondary asthma prevention strategy.
- House dust mite (HDM) sensitization is a common trigger for asthma.
Purpose of the Study:
- To investigate if new feather upper bedding (pillow and quilt) reduces asthma severity in HDM-sensitized children over one year.
- Comparison was made against standard dust mite avoidance advice and mite-occlusive mattress covers.
- The study aimed to provide RCT evidence on feather bedding's role in asthma management.
Main Methods:
- A randomized controlled trial (RCT) was conducted.
- 197 children with moderate-to-severe asthma and HDM sensitization participated.
- Intervention group received feather bedding and a mite-occlusive mattress cover; control group received standard care and a mite-occlusive mattress cover.
Main Results:
- No significant differences were observed between the feather bedding and standard care groups for primary outcomes like frequent wheeze, speech-limiting wheeze, or sleep disturbance due to wheezing.
- Secondary analyses suggested a potential benefit for children sleeping supine, with reduced sleep disturbance and severe wheeze.
- Spirometry and challenge testing also showed no significant group differences.
Conclusions:
- Providing feather upper bedding to children with moderate-to-severe asthma and HDM sensitization did not lead to improved respiratory symptoms or lung function after one year.
- The findings do not support the use of feather bedding as a secondary prevention measure for this patient group.
- Further research may explore specific subgroups or different intervention durations.
Introduction:
Observational studies report inverse associations between the use of feather upper bedding (pillow and/or quilt) and asthma symptoms but there is no randomised controlled trial (RCT) evidence assessing the role of feather upper bedding as a secondary prevention measure.
Objective:
To determine whether, among children not using feather upper bedding, a new feather pillow and feather quilt reduces asthma severity among house dust mite (HDM) sensitised children with asthma over a 1-year period compared with standard dust mite avoidance advice, and giving children a new mite-occlusive mattress cover.
Design:
RCT.
Setting:
The Calvary Hospital in the Australian Capital Territory and the Children's Hospital at Westmead, Sydney, New South Wales.
Patients:
197 children with HDM sensitisation and moderate to severe asthma. Intervention New upper bedding duck feather pillow and quilt and a mite-occlusive mattress cover (feather) versus standard care and a mite-occlusive mattress cover (standard).
Main Outcome Measures:
The proportion of children reporting four or more episodes of wheeze in the past year; an episode of speech-limiting wheeze; or one or more episodes of sleep disturbance caused by wheezing; and spirometry with challenge testing. Statistical analysis included multiple logistic and linear regression.
Results:
No differences between groups were found for primary end points--frequent wheeze (OR 1.51, 95% CI 0.83 to 2.76, p=0.17), speech-limiting wheeze (OR 0.70, 95% CI 0.32 to 1.48, p=0.35), sleep disturbed because of wheezing (OR 1.17, 95% CI 0.64 to 2.13, p=0.61) or for any secondary end points. Secondary analyses indicated the intervention reduced the risk of sleep being disturbed because of wheezing and severe wheeze to a greater extent for children who slept supine.
Conclusion:
No differences in respiratory symptoms or lung function were observed 1 year after children with moderate-severe asthma and HDM sensitisation were given a mite-occlusive mattress cover and then received either feather upper bedding (pillow and quilt) or standard bedding care.
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