Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):

Ultrasonography

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...

Three-Dimensional Microscopy in Microbiology

Three-Dimensional Microscopy in Microbiology

Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...

Imaging Studies II: Ultrasonography

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...

Imaging Biological Samples with Optical Microscopy

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Single-cell RNA sequencing profiles drug activity within spatially engineered 3D cultures.

Nature communications·2026

Same author

A wireless and handheld optical palpation imaging probe for use in breast-conserving surgery.

APL bioengineering·2026

Same author

A Side-viewing Fluorescence Needle Probe for Brain Biopsy Guidance.

IEEE transactions on bio-medical engineering·2026

Same author

Protocol to study murine ovarian elasticity and composition in situ by integrating quantitative micro-elastography with light microscopy.

STAR protocols·2026

Same author

Three-dimensional quantitative micro-elastography reveals alterations in spatial elasticity patterns in murine ovaries during ageing.

Communications biology·2025

Same author

A randomized, double-blind, placebo-controlled phase 1 trial of the topical pan-lysyl oxidase inhibitor PXS-6302 in mature scars.

Science translational medicine·2025

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Quantifying Elastic Properties of Environmental Biofilms using Optical Coherence Elastography

Quantifying Elastic Properties of Environmental Biofilms using Optical Coherence Elastography

Published on: March 1, 2024

In vivo three-dimensional optical coherence elastography.

Brendan F Kennedy¹, Xing Liang, Steven G Adie

¹Optical + Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, Western Australia, Australia. brendank@ee.uwa.edu.au

|April 1, 2011

Summary

This summary is machine-generated.

This study introduces the first 3D optical coherence elastography (OCE) to measure skin

More Related Videos

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Related Experiment Videos

Last Updated: Jun 3, 2026

Quantifying Elastic Properties of Environmental Biofilms using Optical Coherence Elastography

Quantifying Elastic Properties of Environmental Biofilms using Optical Coherence Elastography

Published on: March 1, 2024

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Area of Science:

Biomedical Engineering
Optical Imaging
Dermatology

Background:

Optical coherence elastography (OCE) provides mechanical property mapping.
Previous in vivo OCE studies were limited in speed and dimensionality.

Purpose of the Study:

To develop and validate the first 3D OCE system for in vivo skin analysis.
To investigate the mechanical properties of human skin under varying hydration conditions.

Main Methods:

Utilized a high-speed spectral-domain optical coherence tomography (OCT) system.
Applied uni-axial strain at 125 Hz with a controlled static preload.
Acquired and processed 3D OCE data for normal and hydrated skin.

Main Results:

Achieved >450 times higher line rate compared to previous in vivo OCE.
Demonstrated 3D visualization of mechanical responses in skin.
Observed increased elasticity in the stratum corneum of hydrated skin.

Conclusions:

The developed 3D OCE system enables advanced in vivo skin biomechanics assessment.
Skin hydration significantly influences the elastic properties of the stratum corneum.