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Related Experiment Video

Updated: Jun 3, 2026

MRI and PET in Mouse Models of Myocardial Infarction

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

Emerging MRI methods in translational cardiovascular research.

Moriel H Vandsburger¹, Frederick H Epstein

¹Department of Biological Regulation, Weizmann Institute of Science, 76100, Rehovot, Israel. moriel.vandsburger@gmail.com

Journal of Cardiovascular Translational Research

|April 1, 2011

Summary

Cardiac magnetic resonance imaging (CMR) offers advanced techniques for comprehensive heart assessment. These methods aid translational cardiovascular research, moving discoveries from the lab to patient care.

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Area of Science:

Cardiovascular Imaging
Biomedical Engineering

Background:

Cardiac magnetic resonance imaging (CMR) is the gold standard for assessing left ventricular (LV) structure and function.
Late gadolinium enhancement (LGE) is crucial for imaging myocardial infarction.

Purpose of the Study:

To highlight emerging CMR techniques for advanced cardiovascular research.
To demonstrate the translational potential of CMR from pre-clinical to clinical settings.

Main Methods:

Advanced CMR methods for measuring myocardial edema, ventricular mechanics, fibrosis, and perfusion.
Techniques for cell tracking, molecular imaging, and calcium flux analysis.
MRI for quantifying blood flow velocity and wall shear stress.

Main Results:

Emerging CMR techniques provide comprehensive cardiac examination.
New methods allow detailed assessment of myocardial tissue composition and dynamics.
CMR facilitates tracking of cellular and molecular processes in the heart.

Conclusions:

CMR is a versatile tool for translational cardiovascular research.
Emerging CMR techniques enhance the understanding and diagnosis of heart conditions.
The application of CMR spans from pre-clinical research to clinical patient care.