Related Experiment Video

Updated: Jun 3, 2026

Widespread Transduction of Mouse Neocortical Neurons by Subarachnoid Injection of AAV2
07:40

Widespread Transduction of Mouse Neocortical Neurons by Subarachnoid Injection of AAV2

Published on: May 23, 2025

Adeno-Associated Virus (AAV) Vectors in the CNS

Thomas J McCown1

  • 1UNC Gene Therapy Center, University of North Carolina School of Medicine, Chapel Hill, 27599, USA. thomas_mccown@med.unc.edu

Current Gene Therapy
|April 2, 2011
PubMed
Summary

Adeno-associated virus (AAV) vectors are effective for central nervous system (CNS) gene therapy, offering long-term gene expression in neurons with low toxicity. Different AAV serotypes enhance targeting and overcome immune responses for treating neurological disorders.

More Related Videos

Methods and Tips for Intravenous Administration of Adeno-associated Virus to Rats and Evaluation of Central Nervous System Transduction08:11

Methods and Tips for Intravenous Administration of Adeno-associated Virus to Rats and Evaluation of Central Nervous System Transduction

Published on: August 25, 2017

Production, Purification, and Quality Control for Adeno-associated Virus-based Vectors09:21

Production, Purification, and Quality Control for Adeno-associated Virus-based Vectors

Published on: January 29, 2019

Related Concept Videos