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Related Experiment Video

Updated: Jun 3, 2026

Preparation of Keratin Hydrolysate from Chicken Feathers and Its Application in Cosmetics

Preparation of Keratin Hydrolysate from Chicken Feathers and Its Application in Cosmetics

Published on: November 27, 2017

Water adherence factors for human skin.

Jaspreet S Gujral¹, Deborah M Proctor, Steave H Su

¹Scientific and Regulatory Affairs, Wm. Wrigley Jr. Company, Chicago, IL, USA. jaspreet.gujral@wrigley.com

Risk Analysis : an Official Publication of the Society for Risk Analysis

|April 2, 2011

Summary

Researchers measured water adhering to human skin, a crucial factor for chemical exposure risk assessment. This data is vital for refining dermal dose calculations in environmental risk assessments, especially for splash scenarios.

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Preparation of Keratin Hydrolysate from Chicken Feathers and Its Application in Cosmetics

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Published on: February 23, 2018

Area of Science:

Environmental Science
Toxicology
Dermal Exposure Science

Background:

Chemical exposure via skin contact is a significant environmental health concern.
Accurate dermal dose assessment requires understanding the volume of water adhering to skin.
Existing soil adherence models lack direct applicability to water adherence on human skin.

Purpose of the Study:

To quantify the amount of water that adheres to human skin.
To provide essential data for improving dermal risk assessment models.
To address a gap in current environmental protection agency (EPA) risk assessment guidance.

Main Methods:

Development of novel measurement techniques to quantify water adherence on skin.
Experimental procedures to simulate incidental dermal exposure scenarios.
Data analysis to establish adherence factors for water on human skin.

Main Results:

First-time measurements of water adherence volumes on human skin were obtained.
Quantified adherence factors provide a basis for more realistic exposure modeling.
Results highlight limitations of assuming unlimited chemical availability in certain exposure scenarios.

Conclusions:

Water adherence on skin is a critical, previously unquantified factor in dermal exposure.
The developed measurements will enhance the accuracy of chemical risk assessments.
This research supports improved public health protection from environmental chemical exposures.