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Related Experiment Video

Updated: Jun 3, 2026

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

Intravascular lymphomatosis presenting as acute hemispheric dysfunction.

Woo Sub Hwang¹, Chul Won Jung, Young Hye Ko

¹Department of Neurology, Samsung Medical Center, College of Medicine, Sungkyunkwan University, Seoul, Korea.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association

|April 2, 2011

Summary

This summary is machine-generated.

Intravascular lymphomatosis (IVL) typically affects both brain hemispheres. This case highlights IVL presenting as acute hemispheric dysfunction, expanding its known clinical spectrum.

Related Experiment Videos

Last Updated: Jun 3, 2026

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

Area of Science:

Neurology
Oncology
Pathology

Background:

Intravascular lymphomatosis (IVL) is a rare neoplastic disorder characterized by the proliferation of malignant lymphoid cells within small blood vessels.
IVL commonly presents with neurological symptoms such as seizures or dementia, often affecting both cerebral hemispheres.

Observation:

A 54-year-old male presented with acute neurological deficits suggestive of hemispheric dysfunction.
The patient's condition showed responsiveness to corticosteroid therapy.
Cerebral imaging revealed hypoperfusion in the right hemisphere, indicating localized brain dysfunction.

Findings:

Bone marrow biopsy confirmed the presence of malignant lymphoid cells within blood vessels, establishing the diagnosis of IVL.
This case represents a novel presentation of IVL manifesting as acute, unilateral hemispheric dysfunction.

Implications:

The findings expand the recognized clinical spectrum of Intravascular Lymphomatosis.
This case underscores the importance of considering IVL in the differential diagnosis of acute neurological deficits, even with atypical presentations.
Further research into the diverse manifestations of IVL is warranted to improve early diagnosis and patient outcomes.