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Health care resource use and costs among patients with cushing disease

Brooke Swearingen1, Ning Wu, Shih-Yin Chen

  • 1Neuroendocrine Clinical Center, Massachusetts General Hospital, Boston, Massachusetts, USA. BSwearingen@partners.org

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|April 2, 2011
PubMed

Insights

Patients with Cushing disease incur higher health care costs due to comorbidities. Successful surgery reduces these costs, while unsuccessful surgery increases them, highlighting the economic impact of treatment outcomes.

Area of Science:

  • Endocrinology
  • Health Economics
  • Surgical Outcomes

Background:

  • Cushing disease is associated with significant comorbidities.
  • Understanding the economic burden of Cushing disease is crucial for healthcare planning.

Purpose of the Study:

  • To evaluate healthcare expenditures in Cushing disease patients.
  • To determine the impact of surgical treatment on overall and comorbidity-related costs.

Main Methods:

  • Retrospective cohort study using insurance claims data (2004-2008).
  • Patients with Cushing disease were matched with controls (nonfunctioning pituitary adenomas and population controls).
  • Analysis of comorbidities and annual direct healthcare costs, comparing pre- and post-operative periods based on remission status.

Main Results:

  • Cushing disease patients exhibited higher rates of hypertension, diabetes mellitus, and hyperlipidemia.
  • Total annual healthcare costs were significantly higher for Cushing disease patients compared to controls.
  • Successful surgery led to decreased outpatient costs and a trend of reduced overall costs; unsuccessful surgery correlated with increased postoperative costs.

Conclusions:

  • Cushing disease patients present with more comorbidities and higher healthcare costs.
  • Surgical success in Cushing disease is linked to reduced healthcare expenditures.
  • Treatment failure results in increased healthcare costs, emphasizing the importance of effective surgical intervention.
Abstract

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