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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Structure01:45

Kidney Structure

The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

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Related Experiment Video

Updated: Jun 3, 2026

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
11:47

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

Published on: February 21, 2016

Kidney paired donation.

C Bradley Wallis, Kannan P Samy, Alvin E Roth

    Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
    |April 2, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Kidney paired donation (KPD) facilitates transplants for incompatible donor-recipient pairs, rapidly growing as a kidney source. Challenges include allocation, financing, and integrating altruistic donors into national systems.

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    Last Updated: Jun 3, 2026

    Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
    11:47

    Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

    Published on: February 21, 2016

    Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
    09:15

    Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

    Published on: May 7, 2019

    Robot-Assisted Kidney Transplantation
    07:30

    Robot-Assisted Kidney Transplantation

    Published on: July 19, 2021

    Area of Science:

    • Nephrology
    • Transplantation immunology
    • Health policy

    Background:

    • Kidney paired donation (KPD) emerged in 2000 in the USA, addressing living donor incompatibility.
    • KPD has become the fastest-growing source of transplantable kidneys in the last decade.
    • This review examines KPD concepts and challenges in preparation for a national pilot program.

    Discussion:

    • Various algorithms have been implemented globally to optimize KPD transplants.
    • Growing donor pools necessitate advanced allocation strategies balancing equity and utility.
    • Financing the national KPD system presents a significant challenge beyond philanthropic support.

    Key Insights:

    • KPD overcomes barriers for incompatible living donors.
    • Allocation strategies must balance transplant quality and quantity.
    • Altruistic donors and donation chains are crucial components of KPD.

    Outlook:

    • The USA's national KPD system is in its fifth year of development.
    • Continued innovation in algorithms and policy is essential for KPD expansion.
    • Addressing financial sustainability is critical for the long-term success of national KPD programs.