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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
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Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...

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Related Experiment Video

Updated: Jun 3, 2026

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)
08:18

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)

Published on: December 26, 2015

Functional treatments in multiple sclerosis.

Ardith M Courtney1, Wanda Castro-Borrero, Scott L Davis

  • 1Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-8806, USA.

Current Opinion in Neurology
|April 2, 2011
PubMed
Summary
This summary is machine-generated.

Recent advances in multiple sclerosis (MS) management focus on improving symptoms like gait dysfunction and fatigue. Effective symptom control is crucial for maintaining quality of life when neurologic injury reversal is not possible.

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Related Experiment Videos

Last Updated: Jun 3, 2026

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)
08:18

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)

Published on: December 26, 2015

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
08:48

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Published on: January 29, 2016

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

Area of Science:

  • Neurology
  • Rehabilitation Medicine

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease characterized by a wide range of symptoms and dysfunctions.
  • Effective management of these symptoms is critical for patients' quality of life and functional independence.

Purpose of the Study:

  • To review recent advancements in understanding and managing MS-related symptoms and dysfunctions.
  • To highlight key research findings from the past 1.5 years.

Main Methods:

  • Literature review of research published within the last 18 months.
  • Focus on studies addressing gait, exercise, fatigue, bowel/bladder/sexual dysfunction, and sleep.

Main Results:

  • Functional electrical stimulation and strength training show promise for improving gait and motor function.
  • Exercise training positively impacts mood, quality of life, and reduces inflammation.
  • Progress is being made in understanding and treating fatigue, bowel, bladder, and sexual dysfunction.

Conclusions:

  • Symptom management and functional improvement are essential for mitigating disability in MS.
  • Ongoing basic research and clinical trials offer promising solutions for enhancing patient outcomes.