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Updated: Jun 3, 2026

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure
Published on: May 27, 2022
Cytotoxic metabolites from the soil-derived fungus Exophiala pisciphila
Cui-Cui Wang1, Hai-Zhou Liu, Ming Liu
1Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Abstract:
A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3-4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1-4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher's method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.
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