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Updated: Jun 3, 2026

Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells
Published on: September 30, 2018
Pancreatic endocrine tumors
1Department of Pathology and Ontario Cancer Institute, University Health Network, University of Toronto, Toronto, ON, Canada. sylvia.asa@uhn.on.ca
Abstract:
The endocrine cells of the pancreas and their related cells throughout the gastrointestinal tract give rise to a variety of tumors that pose a diagnostic challenge. There has been progress in understanding their histogenesis, morphology, immunohistochemistry, molecular biology and classifications. This review will focus on nomenclature/terminology, classification, the role of immunohistochemistry, molecular advances, including genetic predisposition, and potential therapeutic targets to define the role of pathology in the application of prognostic and predictive markers for this disease.
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