Drug treatment in schizophrenia : issues of comparability and costs

Pharmacological intervention is the commonest mode of managing patients with schizophrenia. Both clinicians and patients are concerned that antipsyohotic drugs are costly and contribute to poor drug compliance in India. This study compared the equivalent doses of antipsychotic drugs and their costs across brands. Results show that antipsychotic drugs are affordable and are comparable to drug treatment costs of other physical illnesses. However, coprescription of drugs add to the burden. Numerous brands and a 2-2-1/2 fold difference in cost raises many concerns including that of drug bioavailability. Hence, the authors recommend consensus and formulation of guidelines for the pharmacological management of schizophrenia.