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Updated: Jun 3, 2026

Sample Preparation for Probe Electrospray Ionization Mass Spectrometry
Published on: February 19, 2020
Recent directions of electrospray mass spectrometry for elemental speciation analysis
Dirk Schaumlöffel1, Andreas Tholey
1Laboratoire de Chimie Analytique Bio-Inorganique et Environnement/IPREM, Université de Pau et des Pays de l'Adour/CNRS UMR 5254, Hélioparc, 2 av. du Président Angot, 64053 Pau, France. dirk.schaumloeffel@univ-pau.fr
Abstract:
A brief survey is given of the last 2 years' literature on electrospray mass spectrometry (ESI-MS) for speciation analysis. As observed for many years, the main recent applications in this field concern arsenic and selenium species, especially in studies encompassing combined use of molecular and element mass spectrometry. A further application field is the stoichiometric characterization of metal complexes by ESI-MS, which in some studies was assisted by nuclear magnetic resonance spectroscopy. A few examples are presented to illustrate arsenic species involved in metabolic pathways, sulfur species in oils and bitumen, and aluminum complexes. On the basis of this review, we also give an outlook of expected future developments and trends in this research field.
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