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Published on: June 2, 2014
Headache attributable to nonvascular intracranial disorders
Mark Obermann1, Dagny Holle, Steffen Naegel
1Department of Neurology, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany. mark.obermann@uni-due.de
Headache from nonvascular intracranial disorders encompasses diverse conditions like cerebrospinal fluid pressure issues, inflammatory diseases, and neoplasms. These headaches often mimic primary headaches, potentially delaying diagnosis.
Area of Science:
- Neurology
- Neuroscience
Background:
- Headache attributed to nonvascular intracranial disorders includes a wide range of idiopathic and secondary conditions.
- These headaches are defined by their close temporal relationship to an underlying intracranial disorder.
Purpose of the Study:
- To provide an overview of diverse nonvascular intracranial disorders causing headaches.
- To highlight the diagnostic challenges posed by these conditions.
Main Methods:
- Review of existing literature and classification of nonvascular intracranial headache disorders.
- Analysis of clinical presentations and potential causes.
Main Results:
- Identified causes include cerebrospinal fluid pressure abnormalities, noninfectious inflammatory diseases (e.g., neurosarcoidosis, aseptic meningitis), intracranial neoplasms, Chiari malformation type I, and postictal headaches.
- Conditions like hypothalamic/pituitary dysfunction and intrathecal injections are also implicated.
- Clinical presentations frequently mimic primary headaches.
Conclusions:
- Nonvascular intracranial headaches represent a complex group of disorders with varied etiologies.
- The mimicry of primary headaches necessitates careful diagnostic evaluation to avoid delays.
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