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Published on: May 31, 2022
[Peripheral arterial occlusive disease and its care in hemodialysis patients]
Hsing-Wan Chen1, Hsueh-Erh Liu
1Department of Nursing, Chang Gung Institute of technology, School of Nursing, Chang Gung University, ROC.
Insights
Peripheral arterial occlusive disease (PAOD) is common in hemodialysis patients, leading to amputations and higher mortality. Combining ankle-brachial index with other simple tests can improve early detection and patient outcomes.
Area of Science:
- Vascular Medicine
- Nephrology
- Cardiovascular Disease
Context:
- Peripheral arterial occlusive disease (PAOD) is significantly more prevalent in hemodialysis patients compared to the general population.
- PAOD is a primary cause of amputations and increased cardiovascular mortality in this patient group.
- Standard screening tools like the ankle-brachial index (ABI) may be unreliable in hemodialysis patients due to vascular calcification.
Purpose:
- To highlight the high prevalence and severe consequences of PAOD in hemodialysis patients.
- To discuss the limitations of the ankle-brachial index (ABI) in this population.
- To advocate for improved screening methods for early PAOD detection.
Summary:
- Hemodialysis patients exhibit a markedly higher incidence of peripheral arterial occlusive disease (PAOD), contributing to amputations and elevated cardiovascular mortality.
- The ankle-brachial index (ABI), a common screening tool, may underestimate PAOD in hemodialysis patients due to calcified arteries.
- Integrating limb oxygen saturation measurements and the Edinburgh Claudication Questionnaire with ABI can enhance screening accuracy.
Impact:
- Early detection of PAOD through improved screening can lead to timely interventions.
- Risk factor modification, medical management, and exercise rehabilitation are crucial for improving walking function.
- Effective PAOD management in hemodialysis patients can reduce hospitalization rates and mortality.
Abstract:
The prevalence of peripheral arterial occlusive disease (PAOD) in hemodialysis patients is several times higher than among the general population, and is the main reason for amputations in this group. Patients with peripheral arterial occlusive disease face higher hospitalization and mortality rates associated with cardiovascular disease than non-PAOD patients. The ankle brachial index (ABI) is a widely used PAOD screening tool that may under-estimate PAOD prevalence in the hemodialysis population in the presence of extensive vascular calcification. Studies have demonstrated oxygen saturation in the upper and lower limbs and the "Edinburgh Claudication Questionnaire" as simple screening methods that, in combination with ABI, can increase screening test effectiveness. Early PAOD detection, risk factor modification, medical treatment, and exercise rehabilitation therapy can improve walking function and reduce mortality in PAOD patients.
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