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Related Concept Videos

Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Recombinant DNA01:09

Recombinant DNA

Overview
Recombinant DNA01:09

Recombinant DNA

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Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Transgenic Plants02:50

Transgenic Plants

Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...

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Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers
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Published on: August 12, 2014

Biomaterials to gene delivery.

Sung Wan Kim1

  • 1Department of Pharmaceutics, Pharmaceutical Chemistry, University of Utah, 20 South 2030 East, Salt Lake City, Utah 84112-5820, United States.

Journal of Controlled Release : Official Journal of the Controlled Release Society
|April 5, 2011
PubMed
Summary
This summary is machine-generated.

This research summarizes over 40 years of biomaterials investigation. The laboratory

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Area of Science:

  • Biomaterials Science
  • Materials Science
  • Biotechnology

Background:

  • The field of biomaterials has evolved significantly over the past four decades.
  • Laboratory research has been central to advancing biomaterials development.

Purpose of the Study:

  • To provide a concise overview of key research conducted over 40 years.
  • To highlight significant contributions to the field of biomaterials.

Main Methods:

  • Literature review of past laboratory publications.
  • Synthesis of historical research findings.

Main Results:

  • A retrospective analysis of biomaterials research progress.
  • Identification of pivotal studies and innovations from the laboratory.

Conclusions:

  • Biomaterials research has a long and impactful history.
  • Continued innovation in biomaterials is essential for future advancements.