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Updated: Jun 3, 2026

Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes
Published on: July 27, 2018
A systems biology approach to the evolution of plant-virus interactions
Santiago F Elena1, Javier Carrera, Guillermo Rodrigo
1Instituto de Biología Molecular y Celular de Plantas, CSIC-UPV, Ingeniero Fausto Elio s/n, 46022 València, Spain. sfelena@ibmcp.upv.es
Abstract:
Omic approaches to the analysis of plant-virus interactions are becoming increasingly popular. These types of data, in combination with models of interaction networks, will aid in revealing not only host components that are important for the virus life cycle, but also general patterns about the way in which different viruses manipulate host regulation of gene expression for their own benefit and possible mechanisms by which viruses evade host defenses. Here, we review studies identifying host genes regulated by viruses and discuss how these genes integrate in host regulatory and interaction networks, with a particular focus on the physical properties of these networks.
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