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Related Concept Videos

Pericarditis I: Introduction01:22

Pericarditis I: Introduction

Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
Ascites01:19

Ascites

DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...
Peritoneum01:21

Peritoneum

The peritoneum is a vital membrane that lines the abdominal cavity and covers most of the organs within it. It plays a crucial role in protecting the organs, providing a smooth surface for their movement, and facilitating various physiological processes. Understanding the anatomy and function of the peritoneum is essential for comprehending the complexities of the abdominal region.
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Peritoneal Dialysis I: Introduction and Procedure01:30

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Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
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Chronic Pancreatitis I: Introduction

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Related Experiment Video

Updated: Jun 3, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
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Published on: July 20, 2022

Encapsulating peritoneal sclerosis - an overview.

Niko Braun1, Mark Dominik Alscher, Martin Kimmel

  • 1Zentrum für Innere Medizin IV, Abteilung für Allgemeine Innere Medizin und, Nephrologie, Robert-Bosch Krankenhaus, Auerbachstrasse, Stuttgart, Germany. niko.braun@rbk.de

Nephrologie & Therapeutique
|April 5, 2011
PubMed
Summary

Encapsulating peritoneal sclerosis (EPS) is a severe complication of peritoneal dialysis (PD). Early referral to specialized centers and improved diagnostic criteria, including histology, are crucial for better patient outcomes.

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Area of Science:

  • Nephrology
  • Gastroenterology
  • Pathology

Background:

  • Encapsulating peritoneal sclerosis (EPS) is a rare, life-threatening complication of peritoneal dialysis (PD).
  • International guidelines for EPS diagnosis were established in 2000, but evidence for management and diagnosis remains limited.
  • Experience in managing EPS has grown, necessitating updated guidelines and further research.

Purpose of the Study:

  • To highlight the need for improved diagnostic criteria and therapeutic evidence for EPS.
  • To emphasize the importance of early referral to specialized EPS centers.
  • To underscore the role of pathology and experienced surgical management in patient outcomes.

Main Methods:

  • Review of existing literature and clinical experience with EPS.
  • Discussion of diagnostic challenges, including the role of peritoneal biopsies.
  • Identification of risk factors and the need for close patient monitoring.

Main Results:

  • Evidence regarding EPS therapy and diagnosis is still lacking, despite networking efforts.
  • Multicenter trials are essential to establish evidence-based management strategies.
  • Morphology and immunohistochemistry are expected to be crucial for future diagnosis.

Conclusions:

  • Patients at risk for EPS require close monitoring and prompt referral to specialized centers.
  • Clear histological criteria for peritoneal biopsies are needed.
  • Experienced surgical intervention is critical for favorable patient outcomes.