Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fermentation01:29

Fermentation

135.9K
Most eukaryotic organisms require oxygen to survive and function adequately. Such organisms produce large amounts of energy during aerobic respiration by metabolizing glucose and oxygen into carbon dioxide and water. However, most eukaryotes can generate some energy in the absence of oxygen by anaerobic metabolism.
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
135.9K
Stomach pH Regulation01:21

Stomach pH Regulation

7.8K
The human body carefully regulates the internal pH of different organs to maintain homeostasis. For example, while the blood plasma maintains a neutral pH of 7, the stomach lumen has an acidic pH of 1.5 - 3.5. The low pH of stomach lumen helps kill pathogens in the food and break down complex food molecules.
The acid-secreting gastric mucosal epithelial cells (parietal cells) lining the stomach lumen maintain the low pH in the lumen. Numerous ion transporters and channels on these parietal...
7.8K
Taste Buds and Receptors01:20

Taste Buds and Receptors

6.1K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
6.1K
The Physiology of Taste01:24

The Physiology of Taste

8.4K
The perception of a salty flavor is facilitated by sodium ions within the oral salivary fluid. Upon consumption of a salty substance, salt crystals disassemble, leading to the liberation of its constituents—Na+ and Cl- ions. These ions subsequently dissolve into the salivary fluid present in the oral cavity. The external environment of the gustatory cells experiences an elevation in Na+ concentration, thereby establishing a potent concentration gradient. This gradient propels the...
8.4K
Conditioned Taste Aversion01:14

Conditioned Taste Aversion

1.7K
Conditioned taste aversion, also known as sauce béarnaise syndrome, is a phenomenon in which an individual develops an aversion to a certain food taste following a negative experience, typically illness. This form of aversion is a type of classical conditioning in which the taste of the food (conditioned stimulus, CS) is associated with the experience of illness (unconditioned stimulus, UCS).
A notable characteristic of conditioned taste aversion is that it often requires only a single...
1.7K
Primary Motives: Hunger and Thirst01:25

Primary Motives: Hunger and Thirst

1.8K
Hunger and thirst are fundamental physiological drives crucial for maintaining homeostasis and ensuring the survival of both humans and animals. These drives are regulated through complex interactions between the brain, hormones, and sensory receptors.
Hunger arises when the brain detects changes in the body's nutrient levels, including glucose, lipids, amino acids, and hormones such as ghrelin and leptin. The hypothalamus plays a central role in hunger regulation. The lateral hypothalamus...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram.

Nature·2026
Same author

Parallel Pathways for Visual and Olfactory Information in the Mushroom Bodies of the Swallowtail Butterfly Brain.

The Journal of comparative neurology·2026
Same author

Cognitive primitives of the insect brain.

Trends in cognitive sciences·2025
Same author

Sexual dimorphism in the complete connectome of the <i>Drosophila</i> male central nervous system.

bioRxiv : the preprint server for biology·2025
Same author

Object learning: Ball games for flies.

Current biology : CB·2025
Same author

Play-like behavior exhibited by the vinegar fly Drosophila melanogaster.

Current biology : CB·2025

Related Experiment Video

Updated: Apr 13, 2026

Studying Aggression in Drosophila fruit flies
11:06

Studying Aggression in Drosophila fruit flies

Published on: February 25, 2007

16.8K

Hungry flies tune to vinegar.

Wolf Huetteroth1, Scott Waddell

  • 1Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA. cott.waddell@umassmed.edu

Cell
|April 5, 2011
PubMed
Summary
This summary is machine-generated.

Hunger alters the sensitivity of olfactory sensory neurons in fruit flies, enhancing their ability to search for odors. This research reveals how internal states influence sensory perception and behavior.

More Related Videos

Single Sensillum Recordings in the Insects Drosophila melanogaster and Anopheles gambiae
13:27

Single Sensillum Recordings in the Insects Drosophila melanogaster and Anopheles gambiae

Published on: February 17, 2010

26.4K
A Single-fly Assay for Foraging Behavior in Drosophila
13:01

A Single-fly Assay for Foraging Behavior in Drosophila

Published on: November 5, 2013

13.9K

Related Experiment Videos

Last Updated: Apr 13, 2026

Studying Aggression in Drosophila fruit flies
11:06

Studying Aggression in Drosophila fruit flies

Published on: February 25, 2007

16.8K
Single Sensillum Recordings in the Insects Drosophila melanogaster and Anopheles gambiae
13:27

Single Sensillum Recordings in the Insects Drosophila melanogaster and Anopheles gambiae

Published on: February 17, 2010

26.4K
A Single-fly Assay for Foraging Behavior in Drosophila
13:01

A Single-fly Assay for Foraging Behavior in Drosophila

Published on: November 5, 2013

13.9K

Area of Science:

  • Neuroscience
  • Behavioral Biology
  • Sensory Systems

Background:

  • Molecular signals for hunger and satiety are known, but their impact on the nervous system and behavior is less understood.
  • Investigating the neural mechanisms underlying feeding behavior is crucial for understanding organismal responses to internal states.

Discussion:

  • Hunger significantly modulates the sensitivity of olfactory sensory neurons in Drosophila.
  • This heightened sensitivity directly facilitates odor-search behavior, demonstrating a link between internal state and sensory processing.
  • The study highlights the role of specific olfactory pathways in mediating hunger-driven behaviors.

Key Insights:

  • Hunger enhances olfactory sensory neuron sensitivity in fruit flies.
  • This modulation directly promotes odor-seeking behaviors.
  • Provides a neural basis for how internal states influence sensory perception.

Outlook:

  • Further research can explore the specific molecular pathways involved in hunger-induced olfactory modulation.
  • Understanding these mechanisms could offer insights into appetite regulation and sensory processing disorders.
  • Comparative studies in other species may reveal conserved principles of internal state-behavior coupling.