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Published on: January 28, 2021
High-power liquid-lithium target prototype for accelerator-based boron neutron capture therapy.
S Halfon1, M Paul, A Arenshtam
1Soreq NRC, Yavne, Israel. halfon@phys.huji.ac.il
Summary
A novel liquid-lithium target (LiLiT) prototype has been developed for Boron Neutron Capture Therapy (BNCT). This system aims to generate intense neutron flux for medical applications, overcoming thermal power challenges.
Area of Science:
- Nuclear Engineering
- Medical Physics
- Accelerator Technology
Background:
- Boron Neutron Capture Therapy (BNCT) requires intense neutron sources.
- Existing neutron sources face challenges with thermal power management at high beam intensities.
- Accelerator-based neutron sources offer a potential solution for localized BNCT.
Purpose of the Study:
- To develop and test a prototype Liquid-Lithium Target (LiLiT) for accelerator-based neutron generation.
- To address the thermal power dissipation issue in high-intensity proton beam applications.
- To design a system suitable for potential clinical implementation in hospitals.
Main Methods:
- Construction and commissioning of a compact LiLiT prototype.
- Off-line circulation tests to evaluate lithium jet stability.
- Planned testing with high-power electron and proton beams (1.91-2.5 MeV, 2-4 mA).
- Monte Carlo simulations for moderator/reflector design.
Main Results:
- A stable liquid-lithium jet was generated in off-line circulation tests.
- The LiLiT design aims to manage thermal power from high-intensity proton beams.
- Radiological risks associated with Beryllium-7 production are being assessed and managed.
Conclusions:
- The LiLiT prototype shows promise as a compact neutron source for BNCT.
- The system is designed to overcome thermal power limitations of previous methods.
- Further testing and optimization are planned for clinical viability.

