Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery

Non-Intubated Video-Assisted Thoracoscopic Surgery

Published on: May 26, 2023

Lung volume reduction surgery using the NETT selection criteria.

Mark E Ginsburg¹, Byron M Thomashow, Chun K Yip

¹Department of Surgery, Columbia University College of Physicians and Surgeons, Medical Center, New York, New York 10032, USA. meg18@columbia.edu

The Annals of Thoracic Surgery

|April 5, 2011

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Idiopathic pulmonary fibrosis risk loci in East Asian populations mirror those of European populations.

American journal of respiratory and critical care medicine·2026

Same author

Large airway bronchial wash lipidomics as novel biomarkers for chronic lung allograft dysfunction.

The Journal of thoracic and cardiovascular surgery·2026

Same author

Lung retransplantation during the Lung Allocation Score era: Outcomes from a large single center.

JHLT open·2026

Same author

Response to Letter to the Editor CLBP RCT-GSJ-25-1265.

Global spine journal·2025

Same author

Response to Letter to the Editor CLBP RCT-GSJ-25-1283.

Global spine journal·2025

Same author

Multidisciplinary collaborative guidance on the assessment and treatment of patients with Long COVID: A compendium statement.

PM & R : the journal of injury, function, and rehabilitation·2025

Lung volume reduction surgery (LVRS) for emphysema is safe and effective in selected patients, showing significant improvements in lung function and survival rates. This surgical approach sets a benchmark for advanced emphysema treatments.

Area of Science:

Pulmonary Medicine
Thoracic Surgery
Respiratory Physiology

Background:

The National Emphysema Treatment Trial (NETT) established lung volume reduction surgery (LVRS) as safe and effective for specific emphysema patients.
This study applied NETT selection criteria to 49 patients undergoing bilateral LVRS between February 2004 and May 2009.

Purpose of the Study:

To evaluate the safety and efficacy of LVRS in emphysema patients selected using NETT criteria.
To assess midterm clinical outcomes, including survival and lung function, following LVRS.

Main Methods:

Bilateral LVRS was performed via median sternotomy (10 patients) or video-assisted thoracoscopic surgery (39 patients).
Patient selection adhered to NETT inclusion-exclusion criteria, focusing on upper lobe predominant disease and varying exercise capacity.

More Related Videos

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism

Published on: February 14, 2022

Related Experiment Videos

Last Updated: Jun 3, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery

Non-Intubated Video-Assisted Thoracoscopic Surgery

Published on: May 26, 2023

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism

Published on: February 14, 2022

Preoperative assessments included FEV1, DLCO, and BODE index.

Main Results:

No operative or 90-day mortality was observed; median length of stay was 8 days.
Significant improvements were noted in the BODE index (-2.3, p<0.0001) and FEV1 (+286 cc, p<0.0001) one year post-surgery.
Midterm survival rates were high: 0.98 at 1 year and 0.95 at 3 years.

Conclusions:

LVRS, using NETT selection criteria, offers a very low surgical risk and excellent midterm outcomes for advanced emphysema.
Surgical LVRS serves as the gold standard for comparison with emerging nonsurgical treatments for severe emphysema.