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Updated: Jun 3, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Historical perspectives in diagnostic clinical pathology: development of the pregnancy test
David Haarburger1, Tahir S Pillay
1Division of Chemical Pathology, University of Cape Town and NHLS, Groote Schuur Hospital, Cape Town, South Africa.
Abstract:
This is the first in a series of articles dealing with developments in the history of diagnostic pathology and laboratory medicine for the Journal of Clinical Pathology. The pregnancy test kits of today can give an accurate result within 2 min and are as easily available in the laboratory as they are for over-the-counter purchase. Such kits also find a use in the emergency room when dealing with the diagnosis of sudden abdominal pain in a woman of childbearing age. It is not immediately obvious that the simple urine dipstick tests of today reflect the cumulative knowledge of almost a century of reproductive biology, immunology and clinical chemistry.
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