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Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Related Experiment Video

Updated: Jun 3, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

The intraoperative decrease of selenium is associated with the postoperative development of multiorgan dysfunction in

Christian Stoppe1, Gereon Schälte, Rolf Rossaint

  • 1Department of Anaesthesiology, University Hospital, RWTH Aachen, Germany.

Critical Care Medicine
|April 5, 2011
PubMed
Summary
This summary is machine-generated.

Critically ill patients undergoing cardiac surgery experienced significant drops in selenium, copper, and zinc levels. Low postsurgery selenium was linked to multiorgan failure, highlighting its importance in oxidative balance.

Related Experiment Videos

Last Updated: Jun 3, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

Area of Science:

  • Cardiology
  • Trace Element Metabolism
  • Critical Care Medicine

Background:

  • Trace elements like selenium, copper, and zinc are vital for oxidative balance.
  • Depletion of these elements is observed in critically ill patients, correlating with multiorgan dysfunction and mortality.
  • Cardiac surgery with cardiopulmonary bypass induces oxidative stress via ischemia-reperfusion.

Purpose of the Study:

  • To investigate the intraoperative changes in circulating trace elements during cardiac surgery.
  • To determine if a decrease in trace elements is associated with postoperative multiorgan failure.

Main Methods:

  • Prospective observational clinical study involving 60 patients undergoing cardiac surgery with cardiopulmonary bypass.
  • Whole blood concentrations of selenium, copper, and zinc were measured pre- and post-surgery.
  • Patients were categorized based on the development of postoperative organ failure.

Main Results:

  • Preoperative selenium deficiency was common; all patients showed significant reductions in selenium, copper, and zinc post-surgery (p < .001).
  • Seventeen patients had no organ failure, 31 developed single-organ failure, and 12 experienced multiple organ failure.
  • Postoperative selenium levels were independently associated with multiorgan failure (OR 0.8479, p = .0026).

Conclusions:

  • Cardiac surgery leads to a significant intraoperative decrease in antioxidant trace elements.
  • Low selenium concentrations post-surgery are an independent predictor of developing multiorgan failure.