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Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

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Coronary Artery Disease V: Interprofessional Care

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Related Experiment Video

Updated: Jun 3, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

Drug-coated balloons in the lower limb.

T Zeller¹, S Schmitmeier, G Tepe

¹Angiology Division, Heart Center, Bad Krozingen, Germany. thomas.zeller@herzzentrum.de

The Journal of Cardiovascular Surgery

|April 5, 2011

Summary

Drug-coated balloons offer promising results for femoro-popliteal artery lesions, showing improved patency compared to standard angioplasty. This stentless technology is an attractive alternative for peripheral artery disease treatment.

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The Intra-Aortic Balloon Pump

The Intra-Aortic Balloon Pump

Published on: February 5, 2021

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Last Updated: Jun 3, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

The Intra-Aortic Balloon Pump

The Intra-Aortic Balloon Pump

Published on: February 5, 2021

Area of Science:

Vascular surgery
Interventional cardiology
Biomaterials science

Background:

Concerns persist regarding stent implantation in the femoro-popliteal artery.
Stentless technologies achieving comparable or superior results are highly desirable.
Paclitaxel-eluting stents have shown recent positive outcomes but concerns remain.

Purpose of the Study:

To evaluate the efficacy of drug-coated balloons (DCBs) in femoro-popliteal lesions.
To compare DCB outcomes with plain balloon angioplasty and bare metal stents.
To provide an overview of ongoing trials involving DCBs in peripheral arteries.

Main Methods:

Review of randomized studies (THUNDER, FEMPAC, LEVANT 1) on paclitaxel-releasing DCBs.
Analysis of data from ongoing trials evaluating DCBs below the knee (PICCOLO study).
Inclusion of presented data on drug-eluting stents for shorter lesions (YUKON BTK, DESTINY).

Main Results:

DCBs demonstrated significantly improved patency rates in femoro-popliteal lesions versus plain balloon angioplasty.
DCB patency results were comparable to those of most bare metal nitinol stents.
The efficacy of DCBs below the knee is still under evaluation.

Conclusions:

Drug-coated balloons represent a promising stentless technology for femoro-popliteal artery revascularization.
DCBs offer a viable alternative to stenting, with favorable patency rates.
Further evaluation of DCBs, especially below the knee, is ongoing.