Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Air-permeable hydrogels through viscoelastic phase separation of aerogels.

Nature·2026

Same author

Antibiotics stimulate protein transfer to persister cells.

Science (New York, N.Y.)·2026

Same author

Ion-triggered reconfigurable hydrogels with salt-enhanced mechanical and swelling properties via network topological adaptation.

Nature communications·2026

Same author

Implantable living materials autonomously deliver therapeutics using contained engineered bacteria.

Science (New York, N.Y.)·2026

Same author

Rapid fabrication of solvent-compatible NOA 81 microfluidic devices for double-emulsion microfluidics.

Lab on a chip·2026

Same author

Green Oil-in-Water Nanoemulsions for Delivery of Phytochemicals With Pesticidal Activity for Sustainable Food Production and Safety.

Comprehensive reviews in food science and food safety·2026

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Double Emulsion Generation Using a Polydimethylsiloxane (PDMS) Co-axial Flow Focus Device

Double Emulsion Generation Using a Polydimethylsiloxane (PDMS) Co-axial Flow Focus Device

Published on: December 25, 2015

Controllable microfluidic production of multicomponent multiple emulsions.

Wei Wang¹, Rui Xie, Xiao-Jie Ju

¹School of Chemical Engineering, Sichuan University, Chengdu, China.

|April 5, 2011

Summary

This summary is machine-generated.

Researchers developed a scalable microfluidic device using three building blocks for precise control over multicomponent multiple emulsions. This technology allows for tailored droplet generation for advanced applications in delivery and materials science.

More Related Videos

Bilayer Microfluidic Device for Combinatorial Plug Production

Bilayer Microfluidic Device for Combinatorial Plug Production

Published on: December 1, 2023

Manufacture of Concentrated, Lipid-based Oxygen Microbubble Emulsions by High Shear Homogenization and Serial Concentration

Manufacture of Concentrated, Lipid-based Oxygen Microbubble Emulsions by High Shear Homogenization and Serial Concentration

Published on: May 26, 2014

Related Experiment Videos

Last Updated: Jun 3, 2026

Double Emulsion Generation Using a Polydimethylsiloxane (PDMS) Co-axial Flow Focus Device

Double Emulsion Generation Using a Polydimethylsiloxane (PDMS) Co-axial Flow Focus Device

Published on: December 25, 2015

Bilayer Microfluidic Device for Combinatorial Plug Production

Bilayer Microfluidic Device for Combinatorial Plug Production

Published on: December 1, 2023

Manufacture of Concentrated, Lipid-based Oxygen Microbubble Emulsions by High Shear Homogenization and Serial Concentration

Manufacture of Concentrated, Lipid-based Oxygen Microbubble Emulsions by High Shear Homogenization and Serial Concentration

Published on: May 26, 2014

Area of Science:

Microfluidics
Materials Science
Chemical Engineering

Background:

Multicomponent multiple emulsions are crucial for applications requiring precise encapsulation of diverse substances.
Existing methods often lack the scalability and control needed for complex emulsion structures.

Purpose of the Study:

To develop a hierarchical and scalable microfluidic device for controlled generation of multicomponent multiple emulsions.
To demonstrate the precise control over droplet number, ratio, and size within these emulsions.

Main Methods:

A modular microfluidic system was designed using three core building blocks: a drop maker, a connector, and a liquid extractor.
Combinations of these building blocks were used to create hierarchical structures for higher-order emulsions.
The device enabled independent co-encapsulation of distinct contents at each level.

Main Results:

The microfluidic device successfully generated multicomponent multiple emulsions with independently controlled droplet characteristics.
Scalability was achieved by combining building blocks, enabling the creation of complex, higher-order emulsion structures.
Precise control over the number, ratio, and size of encapsulated droplets was demonstrated.

Conclusions:

The developed microfluidic device offers a versatile platform for precise encapsulation of incompatible actives.
This technology facilitates synergistic delivery, controlled biochemical/chemical reactions, and the engineering of multicompartment materials.
The hierarchical and scalable nature of the device opens new avenues for advanced emulsion-based applications.