Related Experiment Video
Updated: Jun 3, 2026

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Smoking prevalence in addiction treatment: a review
Joseph Guydish1, Emma Passalacqua, Barbara Tajima
1Philip R. Lee Institute for Health Policy Studies, University of California San Francisco, 3333 California St., Suite 265, San Francisco, CA 94118, USA. joseph.guydish@ucsf.edu
Introduction:
This review explores whether smoking prevalence in addiction treatment samples exceeds that shown in epidemiological data for persons with alcohol or other drug use disorders and whether smoking may have decreased over time in the addiction treatment population as it has done in the general population.
Methods:
English language papers published between 1987 and 2009 were searched electronically. Forty papers reporting smoking prevalence for addiction treatment samples in the United States were identified, and key predictor variables were abstracted. Random logistic models were used to assess relationships between each individual predictor (year, treatment modality, primary drug treated, government status, and public/private funding status) and smoking prevalence.
Results:
The lowest smoking prevalence aggregated for studies reported in any single year was 65%, well above epidemiological estimates reported among those with alcohol use and drug use disorders. The odds of smoking were higher in methadone maintenance programs (odds ratio [OR] = 2.25, CI = 1.08, 4.68) as compared with outpatient programs. No other variables in the model were significant. Reanalysis omitting recent studies that may represent outliers or confounding with type of treatment showed a small but significant decrease in smoking over time (OR = 0.9891, CI = 0.9888, 0.9893).
Conclusions:
The very high smoking rates reported in addiction treatment samples warrant significant, organized, and systemic response from addiction treatment systems, from agencies that fund and regulate those systems, and from agencies concerned with tobacco control.
Related Concept Videos
Drug Dependence
CNS Depressants: Alcohol and Nicotine
Stress Prevention and Stress Management Techniques IV
Drug Abuse and Addiction: Pharmacological Phenomena
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
