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Adult and Pediatric Porcine Model of Acute Volume Overload
Published on: January 12, 2024
Pathophysiology, diagnosis, and management of pediatric ascites
Matthew J Giefer1, Karen F Murray, Richard B Colletti
1Division of Gastroenterology and Hepatology, Seattle Children's Hospital, and University of Washington, Seattle, WA 98105, USA.
Insights
This review covers pediatric ascites, detailing causes, diagnosis, and management in children. Prompt identification and treatment are crucial for reducing complications and improving outcomes in pediatric ascites.
Area of Science:
- Pediatric Gastroenterology and Hepatology
- Clinical Medicine
Background:
- Ascites in children presents unique diagnostic and therapeutic challenges.
- Understanding the pathophysiology of cirrhotic and non-cirrhotic ascites is essential.
Purpose of the Study:
- To review the physiological mechanisms of pediatric ascites.
- To provide a comprehensive overview of ascites etiologies in children, stratified by age.
- To discuss diagnostic findings and management strategies unique to the pediatric population.
Main Methods:
- Literature review of pediatric ascites.
- Synthesis of information on pathophysiology, etiology, diagnosis, and treatment.
- Stratification of etiologies by patient age.
Main Results:
- Detailed summary of cirrhotic and non-cirrhotic ascites mechanisms.
- Comprehensive list of pediatric ascites causes.
- Emphasis on age-specific findings in physical examination, imaging, and paracentesis.
- Overview of medical and surgical treatment options.
Conclusions:
- Pediatric ascites requires specialized diagnostic and management approaches.
- Timely diagnosis and effective treatment are critical for minimizing morbidity and mortality in children with ascites.
Abstract:
The pediatric population has a number of unique considerations related to the diagnosis and treatment of ascites. This review summarizes the physiologic mechanisms for cirrhotic and noncirrhotic ascites and provides a comprehensive list of reported etiologies stratified by the patient's age. Characteristic findings on physical examination, diagnostic imaging, and abdominal paracentesis are also reviewed, with particular attention to those aspects that are unique to children. Medical and surgical treatments of ascites are discussed. Both prompt diagnosis and appropriate management of ascites are required to avoid associated morbidity and mortality.
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