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Incidence of gastroesophageal reflux during transpyloric feeds

Rachel Rosen1, Kristen Hart, Mary Warlaumont

  • 1Center for Motility and Functional Gastrointestinal Disorders, Children's Hospital Boston, Boston, MA 02115, USA. rachel.rosen@childrens.harvard.edu

Journal of Pediatric Gastroenterology and Nutrition
|April 6, 2011
PubMed

Insights

Transpyloric feeding in children shows increased reflux events during feeding periods compared to nonfeeding periods. This may explain ongoing hospitalizations despite this feeding method.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Motility Disorders

Background:

  • Transpyloric feeding is a proposed method to manage gastroesophageal reflux.
  • Limited pediatric research exists on its impact on reflux burden.

Purpose of the Study:

  • To assess the reflux burden in pediatric patients undergoing transpyloric feeding.
  • To evaluate the effect of transpyloric feeding on gastroesophageal reflux.

Main Methods:

  • Retrospective review of multichannel intraluminal impedance (MII) tracings in pediatric patients.
  • Comparison of reflux profiles during feeding versus nonfeeding periods.
  • Analysis of reflux-related hospitalizations before and after transpyloric feeding initiation.

Main Results:

  • A trend towards more reflux events per hour during feeding periods (1.4) versus nonfeeding periods (0.8) was observed (P=0.06).
  • No significant difference in esophageal bolus presence time between feeding (1.0%) and nonfeeding (0.6%) periods (P=0.5).
  • No significant change in mean reflux-related hospitalizations before (1.2) and after (1.4) transpyloric feeding (P=0.7).

Conclusions:

  • Transpyloric feeding periods are associated with a higher reflux burden.
  • This increased reflux may contribute to persistent reflux-related hospitalizations in some pediatric patients.
  • Further investigation into optimizing transpyloric feeding strategies for reflux control is warranted.
Abstract

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