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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Headaches during pregnancy.

Rossella E Nappi¹, Francesca Albani, Grazia Sances

¹Research Center for Reproductive Medicine, Section of Obstetrics and Gynecology, Department of Morphological, Eidological and Clinical Sciences, University of Pavia, IRCCS Policlinico San Matteo, Piazzale Golgi 2, Pavia 27100, Italy. renappi@tin.it

Current Pain and Headache Reports

|April 6, 2011

Summary

Migraine without aura significantly improves during pregnancy, unlike migraine with aura. Postpartum breastfeeding also protects against migraine recurrence, but persistent migraine may impact neonatal outcomes.

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Area of Science:

Neurology
Obstetrics
Reproductive Endocrinology

Background:

Migraine is highly sensitive to ovarian hormonal changes.
Pregnancy significantly alters the hormonal milieu, impacting migraine patterns.
Migraine without aura (MO) and migraine with aura (MA) exhibit different responses to hormonal shifts.

Purpose of the Study:

To analyze the distinct effects of pregnancy on migraine without aura (MO) and migraine with aura (MA).
To investigate the influence of postpartum factors, such as breastfeeding, on migraine recurrence.
To explore the potential associations between persistent migraine during pregnancy and adverse neonatal or maternal outcomes.

Main Methods:

Review of existing literature and clinical observations on migraine during pregnancy.
Analysis of reported changes in MO and MA frequency and severity across gestation.
Examination of data on migraine recurrence postpartum and its relation to breastfeeding.

Main Results:

Migraine without aura (MO) shows marked improvement during pregnancy, with most cases remitting by the third trimester.
Migraine with aura (MA) shows less improvement, with some women experiencing new onset aura during gestation.
Breastfeeding demonstrates a protective effect against migraine recurrence after delivery.
Persistent migraine during pregnancy is linked to increased risks of gestational hypertension, preeclampsia, and adverse neonatal outcomes.

Conclusions:

Pregnancy exerts differential effects on MO and MA, with MO benefiting significantly from hormonal stability.
Postpartum breastfeeding is a protective factor for migraine sufferers.
The persistence of migraine throughout gestation warrants attention due to potential associations with maternal vascular complications and neonatal risks.