Related Experiment Video

Updated: Jun 3, 2026

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
07:01

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

[Pediatric injuries from mass casualty events in Israel: a ten-year summary]

Yehezkel Waisman1, Sharon Goldman, Oded Poznanski

  • 1Unit of Emergency Medicine, Schneider Children's Medical Center of Israel, Petah Tikva. waisy@clalit.org.il

Harefuah
|April 7, 2011
PubMed

Insights

Children injured in mass casualty events (MCEs) face significantly higher morbidity and mortality. Terror attacks and motor vehicle collisions are leading causes of severe pediatric MCE injuries, necessitating improved pre-hospital and hospital care.

Area of Science:

  • Pediatric Trauma
  • Mass Casualty Events
  • Injury Epidemiology

Context:

  • Children are uniquely vulnerable during mass casualty events (MCEs).
  • Limited data exists on the specific characteristics of MCE-related injuries in pediatric populations.
  • Understanding these injuries is crucial for developing targeted interventions.

Purpose:

  • To characterize childhood injuries from MCEs in Israel.
  • To analyze injury magnitude, mechanisms, severity, and hospital resource utilization.
  • To provide data for improving pediatric MCE outcomes.

Summary:

  • A descriptive study analyzed 267 hospitalized children (0-17 years) from 75 MCEs (1998-2007) in the Israel Trauma Registry.
  • Terror-related incidents (63%) and motor vehicle collisions (32%) were primary injury mechanisms.
  • Head and neck injuries were most common (67%); 29% sustained severe to fatal injuries (ISS ≥16), with significantly higher mortality and resource use compared to non-MCE injuries.

Impact:

  • MCE-related injuries in children result in substantially higher morbidity and mortality compared to other injury types.
  • Severe injuries, mortality, surgical procedures, ICU admissions, and hospital stays were all significantly elevated for MCEs.
  • Findings underscore the need for enhanced pediatric pre-hospital and hospital resources for MCEs.
Abstract

More Related Videos

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury09:49

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Published on: January 20, 2023

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion10:31

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

Published on: September 25, 2014

Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Cellular Injury II: Classification01:21

Cellular Injury II: Classification

Cellular injury is any process that disrupts a cell’s ability to maintain homeostasis, leading to structural or functional changes. It is broadly classified based on etiology (cause) and mechanism of damage.Classification by EtiologyCellular injury may result from several causes. Hypoxic injury happens due to reduced oxygen delivery, most commonly from inadequate blood supply, such as arterial obstruction; for example, coronary artery thrombosis can cause myocardial infarction. Chemical injury...
Cellular Injury I: Introduction01:00

Cellular Injury I: Introduction

Cellular injury occurs when a cell cannot maintain homeostasis or adapt to stressors such as hypoxia, toxins, or trauma. Depending on severity and duration, injury may be reversible, allowing recovery, or irreversible, leading to cell death.General Mechanisms of Cell InjuryAlthough causes vary, most cellular injuries arise from a few key mechanisms that disrupt essential functions and often amplify one another. Cell survival depends on the extent and balance of these disturbances.ATP depletion...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...