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Xanthogranulomatous pancreatitis presents as a solid tumor mass: a case report
Han-Seong Kim1, Mee Joo, Sun Hee Chang
1Department of Pathology, Inje University Ilsan Paik Hospital, 170 Juhwa-ro, Ilsanseo-gu, Goyang, Korea. hskim@paik.ac.kr
Journal of Korean Medical Science
|April 7, 2011
Summary
Xanthogranulomatous pancreatitis (XGP) is an extremely rare condition. This case report highlights XGP in a 70-year-old woman, emphasizing its consideration in pancreatic mass differentials.
Area of Science:
- Gastroenterology
- Pathology
- Oncology
Background:
- Xanthogranulomatous inflammation (XGI) is a rare idiopathic condition characterized by lipid-laden histiocyte deposition.
- XGI commonly affects organs like the gallbladder, kidney, and stomach, but xanthogranulomatous pancreatitis (XGP) is exceptionally rare.
Observation:
- A 70-year-old woman presented with several months of abdominal pain.
- CT scan revealed a pancreatic mass in the uncinate process, initially suspected as malignant.
- The patient underwent Whipple's operation for the pancreatic mass.
Findings:
- The final pathological diagnosis confirmed xanthogranulomatous pancreatitis (XGP).
- The patient experienced an uneventful post-operative recovery.
- No recurrence of XGP was observed within a 7-month follow-up period.
Implications:
- Xanthogranulomatous pancreatitis (XGP) should be included in the differential diagnosis for pancreatic masses.
- This case underscores the importance of considering rare conditions when typical pancreatic neoplasms are not evident.
- Accurate diagnosis of XGP is crucial for appropriate patient management and prognosis.

