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Updated: Jun 3, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Fungal keratitis.

Sonal S Tuli1

  • 1University of Florida, Gainesville, FL, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|April 7, 2011
PubMed
Summary
This summary is machine-generated.

The best management for fungal keratitis involves topical medications like Natamycin or Amphotericin B. Voriconazole is increasingly preferred for its broad coverage and corneal penetration, with therapy lasting about four weeks.

Keywords:
antifungal medicationsdebridementfungal keratitiskeratomycosis

Related Experiment Videos

Last Updated: Jun 3, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Fungal keratitis is a serious eye infection.
  • Traditional treatments include topical Natamycin for filamentous fungi and Amphotericin B for yeast.

Purpose of the Study:

  • To determine the most appropriate management strategy for fungal keratitis.

Main Methods:

  • Review of current treatment protocols for fungal keratitis.
  • Consideration of medication properties like spectrum of coverage and corneal penetration.
  • Surgical debridement of corneal ulcers is recommended to enhance topical medication penetration.

Main Results:

  • Voriconazole is emerging as a preferred agent for all types of fungal keratitis.
  • Its broad-spectrum activity and enhanced corneal penetration offer advantages over traditional therapies.
  • Treatment duration typically extends to approximately four weeks.

Conclusions:

  • Voriconazole represents a significant advancement in the management of fungal keratitis.
  • Prompt referral to specialized centers is crucial for large or central ulcers.
  • Aggressive debridement and prolonged therapy are key components of successful treatment.