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Updated: Mar 28, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
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Physiologic and pathologic septal deviations: subjective and objective functional rhinologic findings.

G Gogniashvilli1, E Steinmeier, G Mlynski

  • 1Department of Otorhinolaryngology, Institute Ltd Academician N. Kipshidze Central University Clinic, Tbilisi, Georgia, USA.

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|April 7, 2011
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Summary
This summary is machine-generated.

Physiological septal deviation can be distinguished from pathological septal deviation using nasal resistance measurements. This objective method correlates with subjective breathing assessments and endoscopic findings, improving diagnostic accuracy.

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Area of Science:

  • Otolaryngology
  • Rhinology
  • Medical Physiology

Background:

  • Septal deviation is common, with high inter-rater variability in diagnosis.
  • Distinguishing physiological from pathological septal deviation is clinically important.
  • Nasal resistance may offer an objective measure to differentiate septal deviation types.

Purpose of the Study:

  • To differentiate physiological and pathological septal deviation using nasal resistance.
  • To compare objective and subjective parameters between groups.
  • To establish a benchmark for nasal resistance in healthy and deviated septa.

Main Methods:

  • Prospective cohort study of 356 patients.
  • Assessment using rhinoresistometry, acoustic rhinometry, and endoscopy.
  • Definition of a nasal resistance benchmark (≤0.35 sPa/cm^3 at 250 cm^3/s flow-velocity).

Main Results:

  • A benchmark for normal nasal resistance was established (≤0.35 sPa/cm^3 at 250 cm^3/s).
  • 114 subjects had physiological nasal resistance, and 44 had pathological septal deviation.
  • Patients with physiological septal deviation showed similarities to healthy subjects, while pathological cases resembled rhinological patients.

Conclusions:

  • Inspiratory nasal resistance can differentiate physiological from pathological septal deviation.
  • The established benchmark correlates with subjective and endoscopic findings.
  • Rhinoresistometry provides an objective tool for assessing septal deviation.