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Preparation and use of double-labelled enterobactin
C P Bergstrom1, M C Lu, C L Bell
1Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois, Chicago 60612.
Gaoxiong Yi Xue Ke Xue Za Zhi = the Kaohsiung Journal of Medical Sciences
|October 1, 1990
Abstract:
Double-labelled 3H/14C-enterobactin was isolated from bacterial cultures, and evaluated as a potential tool for studying the mammalian metabolism of this iron chelator. Microbial yields were low, but adequate, with a final 3H/14C ratio of 2.95 to 1. Studies conducted with mice indicated that considerable metabolism and rapid elimination of an intraperitoneally injected sample had occurred in 24 hours.