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Immunization and nutritional profile of cases with atraumatic microbial keratitis in preschool age group

Vishal Jhanji1, Prashant Naithani, Ecosse Lamoureux

  • 1Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

American Journal of Ophthalmology
|April 8, 2011
PubMed

Insights

Protein-energy malnutrition and incomplete immunization increase the risk of severe microbial keratitis in young children. Early intervention and nutritional support are crucial for preventing vision loss and the need for corneal transplantation.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Infectious Diseases

Background:

  • Microbial keratitis is a significant cause of vision impairment in children.
  • Atraumatic microbial keratitis in preschool children presents unique challenges in diagnosis and management.
  • The role of nutritional status and vaccination coverage in these cases requires further elucidation.

Purpose of the Study:

  • To investigate the association between protein-energy malnutrition and immunization status and the occurrence of atraumatic microbial keratitis.
  • To identify risk factors contributing to the severity and outcomes of microbial keratitis in preschool children.
  • To evaluate the need for surgical intervention, such as corneal transplantation, in affected children.

Main Methods:

  • A retrospective case analysis was conducted on children aged 5 years or younger.
  • Data on protein-energy malnutrition, immunization profile, and microbiological findings were collected.
  • Outcomes, including the need for corneal transplantation, were assessed.

Main Results:

  • Severe protein-energy malnutrition was significantly linked to bilateral keratitis and incomplete immunization.
  • Bacterial pathogens were identified in 82% of cases, with Staphylococcus species being most common.
  • Children with severe malnutrition were more likely to require corneal transplantation.

Conclusions:

  • Protein-energy malnutrition and suboptimal immunization are associated with atraumatic microbial keratitis in preschool children.
  • These factors contribute to disease severity and the need for corneal transplantation.
  • Addressing nutritional deficiencies and ensuring complete immunization are vital for preventing severe ocular outcomes.
Abstract

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